DDR1 Recombinant Monoclonal Antibody [7F6]

Background
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing (By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.

Description
DDR1 Recombinant Monoclonal Antibody [7F6]. Unconjugated. Raised in: HEK293F Cell.

Formulation
Buffer: 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
hIgG1

Uniprot ID
Q08345

Purification
Affinity Chromatography

Immunogen
Recombinant Human DDR1 protein

Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Alternative Names
CAK antibody; CD 167 antibody; CD167 antibody; CD167 antigen-like family member A antibody; CD167a antibody; Cell adhesion kinase antibody; DDR 1 antibody; DDR antibody; DDR1 antibody; DDR1_HUMAN antibody; Discoidin domain receptor antibody; Discoidin domain receptor tyrosine kinase 1 antibody; Discoidin receptor tyrosine kinase antibody; Discoidin receptor tyrosine kinase isoform a antibody; EDDR 1 antibody; EDDR1 antibody; Epithelial discoidin domain receptor 1 antibody; Epithelial discoidin domain-containing receptor 1 antibody; Epithelial specific receptor kinase antibody; HGK2 antibody; Mammarian carcinoma kinase 10 antibody; Mammary carcinoma kinase 10 antibody; MCK-10 antibody; MCK10 antibody; NEP antibody; Neuroepithelial tyrosine kinase antibody; Neurotrophic tyrosine kinase receptor type 4 antibody; NTRK 4 antibody; NTRK4 antibody; OTTHUMP00000029343 antibody; OTTHUMP00000029344 antibody; OTTHUMP00000029345 antibody; OTTHUMP00000029346 antibody; OTTHUMP00000029347 antibody; OTTHUMP00000164863 antibody; OTTHUMP00000164867 antibody; OTTHUMP00000222080 antibody; Protein-tyrosine kinase 3A antibody; Protein-tyrosine kinase RTK-6 antibody; PTK 3 antibody; PTK 3A protein tyrosine kinase 3A antibody; PTK3 antibody; PTK3A antibody; Receptor tyrosine kinase NEP antibody; RTK 6 antibody; RTK6 antibody; TRK E antibody; TRKE antibody; Tyrosine kinase DDR antibody; Tyrosine kinase receptor E antibody; Tyrosine-protein kinase CAK antibody

Application
ELISA