Kit Box Character Contest  Make your EpiGentek box “alive” and win a $1500 grant for antibodies plus more! » Learn More
Epigentek Home
 
EpiGentek Guarantee

CDK4 Polyclonal Antibody, HRP Conjugated

Share:

Write a Review
Application: ELISA
Areas of Research: Cell Cycle
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
100% Guarantee: 6 months
Catalog No.SizePriceQty
A52391-05050 µg $256.00 
A52391-100100 µg $359.00 
Why EpiGentek AntibodiesFree Shipping on Antibodies
Order now & get it by Tuesday, September 10th  
Product Overview

Background
Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also phosphorylates SMAD3 in a cell-cycle-dependent manner and represses its transcriptional activity. Component of the ternary complex, cyclin D/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.

Description
CDK4 Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
P11802

Purification
>95%, Protein G purified

Immunogen
Recombinant Human Cyclin-dependent kinase 4 protein (2-303AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
Cell division protein kinase 4, PSK-J3, CDK4

Application
ELISA

User Guide & MSDS

[User Guide]*
*Always use the actual User Guide that shipped with your product. Is the above file locked? You can also request user guides by emailing info@epigentek.com along with your contact information and institution name.

Phone Wallet and Stand Give-a-way
Related Products
Terms & Conditions | Privacy Policy | Site Map
Copyright © 2019 EpiGentek Group Inc. All rights reserved.