BackgroundControls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component.
DescriptionC4BPA Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDP04003
Purification>95%, Protein G purified
ImmunogenRecombinant Human C4b-binding protein alpha chain protein (49-597AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesC4b-binding protein alpha chain, C4bp, Proline-rich protein, PRP, C4BPA, C4BP
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000