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Birc5 Polyclonal Antibody, FITC Conjugated

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Application: ELISA
Areas of Research: Apoptosis & Cell Death, Cell Cycle
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Mouse
100% Guarantee: 6 months
Catalog No.SizePriceQty
A56489-05050 µg $256.00 
A56489-100100 µg $359.00 
Availability: Usually Ships Within 1-2 Weeks 
Product Overview

Background
Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. May counteract a default induction of apoptosis in G2/M phase. The acetylated form represses STAT3 transactivation of target gene promoters. May play a role in neoplasia. Inhibitor of CASP3 and CASP7.

Description
Birc5 Polyclonal Antibody, FITC Conjugated. FITC. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Mouse

Isotype
IgG

Uniprot ID
O70201

Purification
>95%, Protein G purified

Immunogen
Recombinant Mouse Baculoviral IAP repeat-containing protein 5 protein (1-140AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
Apoptosis inhibitor 4, Apoptosis inhibitor survivin, TIAP, Api4, Iap4, Birc5

Application
ELISA

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