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ATG8 Polyclonal Antibody

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Application: ELISA
Areas of Research: Apoptosis & Cell Death
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Candida glabrata
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A65370-02020 µg $99.00 
A65370-05050 µg $256.00 
A65370-100100 µg $359.00 
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Product Overview

Background
Ubiquitin-like modifier involved in cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes formation. With ATG4, mediates the delivery of the vesicles and autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.

Description
ATG8 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Candida glabrata

Isotype
IgG

Uniprot ID
Q6FXR8

Purification
>95%, Protein G purified

Immunogen
Recombinant Candida glabrata Autophagy-related protein 8 protein (1-116AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
Autophagy-related protein 8, Autophagy-related ubiquitin-like modifier ATG8, ATG8, AUT7, CAGL0A04675g

Application
ELISA

User Guide & MSDS

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