BackgroundAlpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. The dissociation is voltage-dependent. This toxin is active on insects. It is also highly toxic to crustaceans and has a measurable but low toxicity to mice.
DescriptionAlpha-insect Toxin LqhaIT Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, pH 7.4.
SpecificityLeiurus quinquestriatus hebraeus
IsotypeIgG
Uniprot IDP17728
Purification>95%, Protein G purified
ImmunogenRecombinant Leiurus quinquestriatus hebraeus Alpha-insect toxin LqhaIT protein (20-85AA)
StorageShipped at 4°C. Upon receipt, store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesAlpha-insect toxin LqhaIT,
ApplicationELISA