This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
ACADM Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Human, Mouse, Rat
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ACADM (NP_000007.1).
Shipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
ACADM; ACAD1; MCAD; MCADH; acyl-CoA dehydrogenase, C-4 to C-12 straight chain
WB, IHC, IF; Recommended dilution: WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200