BackgroundDrug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair.
DescriptionABCB5 Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ2M3G0
Purification>95%, Protein G purified
ImmunogenRecombinant Human ATP-binding cassette sub-family B member 5 protein (547-760AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesATP-binding cassette sub-family B member 5, ABCB5, ABCB5 P-gp, P-glycoprotein ABCB5
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000