BackgroundParticipates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
DescriptionTLR5 Recombinant Monoclonal Antibody [10D8]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDO60602
PurificationAffinity-chromatography
ImmunogenA synthesized peptide derived from human TLR5
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesToll-like receptor 5 (Toll/interleukin-1 receptor-like protein 3), TLR5, TIL3
ApplicationELISA, WB; Recommended dilution: WB:1:500-1:5000