SLC1A2 Recombinant Monoclonal Antibody [28F9]

Background
Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate (By similarity).

Description
SLC1A2 Recombinant Monoclonal Antibody [28F9]. Unconjugated. Raised in: HEK293F Cell.

Formulation
Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Specificity
Human

Isotype
Rabbit IgG

Uniprot ID
P43004

Purification
Affinity Chromatography

Immunogen
A synthesized peptide derived from Human SLC1A2

Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Alternative Names
Excitatory amino acid transporter 2 (Glutamate/aspartate transporter II) (Sodium-dependent glutamate/aspartate transporter 2) (Solute carrier family 1 member 2), SLC1A2, EAAT2 GLT1

Application
ELISA, WB, FC; Recommended dilution: WB:1:500-1:2000, FC:1:50-1:200