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Introduction to Epigenetics

Nucleotide Metabolism Antibodies

Purine and pyrimidine nucleotides are the subunits of nucleic acids, DNA and RNA, and are the precursors of nucleotide cofactors, such as NAD. Nucleotide metabolism involves the synthesis and degradation of nucleotides, which are formed from a phosphate, pentose sugar (ribose or 2-deoxyribose), and a nitrogenous base (a purine or pyrimidine). Two major pathways are involved in the synthesis of nucleotides, the de novo pathway and the salvage pathway. Nucleotides are synthesized by the de novo pathway using amino acids, CO2, and tetrahydrofolate. The salvage pathway interconverts nucleosides and nucleotides and recycles purine and pyrimidine bases released as by-products from the breakdown of nucleotides and cofactors during cellular metabolism. The salvage pathway uses a smaller amount of energy than the de novo synthesis pathway.

The purine bases are adenine and guanine, while the pyrimidine bases are thymine, cytosine, and uracil. They form the adenosine and guanosine nucleosides, and the thymidine, cytidine and uridine nucleosides, respectively. RNA is a polymer that can contain all the nucleotides, while DNA does not contain uridine. Adding one or more phosphates to the nucleoside forms a nucleotide. The nitrogenous base constitutes the main difference between the purine and pyrimidine nucleotides, and therefore their synthesis is catalyzed by different routes. However, purine and pyrimidine synthesis, both require the use of phosphoribosyl pyrophosphate (PRPP) which donates the ribose sugar and phosphate needed to form the nucleotide. The breakdown or catabolism of pyrimidine leads to several products, that can be used for fatty acid synthesis or enter the urea cycle; while the breakdown of purine nucleotides leads to one final product, uric acid, which is insoluble and excreted in urine. High levels of uric acid can lead to gout, which involves the accumulation of uric acid crystals in joints. Deficiency or genetic defects in the enzymes involved in nucleotide metabolism often results in several diseases, such as deficiency of adenine deaminase, which leads to severe combined immunodeficiency (SCID).
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GMPR2 Polyclonal Antibody, Biotin Conjugated
GMPR2 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A51320-05050 µg $256.00 Add to Cart
A51320-100100 µg $359.00 Add to Cart
Antibodies
GMPR2 Polyclonal Antibody, FITC Conjugated
GMPR2 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A51319-05050 µg $256.00 Add to Cart
A51319-100100 µg $359.00 Add to Cart
Antibodies
GMPR2 Polyclonal Antibody, HRP Conjugated
GMPR2 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A51318-05050 µg $256.00 Add to Cart
A51318-100100 µg $359.00 Add to Cart
Antibodies
HDDC3 Polyclonal Antibody
HDDC3 Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human, Mouse
Trial Size Available: Yes
A51085-02020 µg $59.00 Add to Cart
A51085-05050 µg $256.00 Add to Cart
A51085-100100 µg $359.00 Add to Cart
Antibodies
HDDC3 Polyclonal Antibody, Biotin Conjugated
HDDC3 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A51088-05050 µg $256.00 Add to Cart
A51088-100100 µg $359.00 Add to Cart
Antibodies
HDDC3 Polyclonal Antibody, FITC Conjugated
HDDC3 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A51087-05050 µg $256.00 Add to Cart
A51087-100100 µg $359.00 Add to Cart
Antibodies
HDDC3 Polyclonal Antibody, HRP Conjugated
HDDC3 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A51086-05050 µg $256.00 Add to Cart
A51086-100100 µg $359.00 Add to Cart
Antibodies
HPRT1 Polyclonal Antibody
HPRT1 Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A52336-02020 µg $59.00 Add to Cart
A52336-05050 µg $256.00 Add to Cart
A52336-100100 µg $359.00 Add to Cart
Antibodies
HPRT1 Polyclonal Antibody, Biotin Conjugated
HPRT1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A52333-05050 µg $256.00 Add to Cart
A52333-100100 µg $359.00 Add to Cart
Antibodies
HPRT1 Polyclonal Antibody, FITC Conjugated
HPRT1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A52334-05050 µg $256.00 Add to Cart
A52334-100100 µg $359.00 Add to Cart
Antibodies
HPRT1 Polyclonal Antibody, HRP Conjugated
HPRT1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A52335-05050 µg $256.00 Add to Cart
A52335-100100 µg $359.00 Add to Cart
Antibodies
IMPDH2 Polyclonal Antibody
IMPDH2 Polyclonal Antibody

Application: ELISA, IF, IHC, WB
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A57797-02020 µg $59.00 Add to Cart
A57797-05050 µg $256.00 Add to Cart
A57797-100100 µg $359.00 Add to Cart
Antibodies
IMPDH2 Polyclonal Antibody
IMPDH2 Polyclonal Antibody

Application: ELISA, IF, IHC, WB
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human, Mouse
Trial Size Available: Yes
A59478-02020 µg $59.00 Add to Cart
A59478-05050 µg $256.00 Add to Cart
A59478-100100 µg $359.00 Add to Cart
Antibodies
IMPDH2 Polyclonal Antibody, Biotin Conjugated
IMPDH2 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A59479-05050 µg $256.00 Add to Cart
A59479-100100 µg $359.00 Add to Cart
Antibodies
IMPDH2 Polyclonal Antibody, Biotin Conjugated
IMPDH2 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A57800-05050 µg $256.00 Add to Cart
A57800-100100 µg $359.00 Add to Cart
Antibodies
IMPDH2 Polyclonal Antibody, FITC Conjugated
IMPDH2 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A59480-05050 µg $256.00 Add to Cart
A59480-100100 µg $359.00 Add to Cart
Antibodies
IMPDH2 Polyclonal Antibody, FITC Conjugated
IMPDH2 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A57799-05050 µg $256.00 Add to Cart
A57799-100100 µg $359.00 Add to Cart
Antibodies
IMPDH2 Polyclonal Antibody, HRP Conjugated
IMPDH2 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A59481-05050 µg $256.00 Add to Cart
A59481-100100 µg $359.00 Add to Cart
Antibodies
IMPDH2 Polyclonal Antibody, HRP Conjugated
IMPDH2 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A57798-05050 µg $256.00 Add to Cart
A57798-100100 µg $359.00 Add to Cart
Antibodies
nrdA Polyclonal Antibody
nrdA Polyclonal Antibody

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Escherichia coli
Trial Size Available: Yes
A50813-02020 µg $59.00 Add to Cart
A50813-05050 µg $256.00 Add to Cart
A50813-100100 µg $359.00 Add to Cart
Antibodies
Result Pages: [<< Prev]   1  2  3  4  5 ...  [Next >>]  Displaying 81 to 100 (of 211 products)
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