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Introduction to Epigenetics

Nucleotide Metabolism Antibodies

Purine and pyrimidine nucleotides are the subunits of nucleic acids, DNA and RNA, and are the precursors of nucleotide cofactors, such as NAD. Nucleotide metabolism involves the synthesis and degradation of nucleotides, which are formed from a phosphate, pentose sugar (ribose or 2-deoxyribose), and a nitrogenous base (a purine or pyrimidine). Two major pathways are involved in the synthesis of nucleotides, the de novo pathway and the salvage pathway. Nucleotides are synthesized by the de novo pathway using amino acids, CO2, and tetrahydrofolate. The salvage pathway interconverts nucleosides and nucleotides and recycles purine and pyrimidine bases released as by-products from the breakdown of nucleotides and cofactors during cellular metabolism. The salvage pathway uses a smaller amount of energy than the de novo synthesis pathway.

The purine bases are adenine and guanine, while the pyrimidine bases are thymine, cytosine, and uracil. They form the adenosine and guanosine nucleosides, and the thymidine, cytidine and uridine nucleosides, respectively. RNA is a polymer that can contain all the nucleotides, while DNA does not contain uridine. Adding one or more phosphates to the nucleoside forms a nucleotide. The nitrogenous base constitutes the main difference between the purine and pyrimidine nucleotides, and therefore their synthesis is catalyzed by different routes. However, purine and pyrimidine synthesis, both require the use of phosphoribosyl pyrophosphate (PRPP) which donates the ribose sugar and phosphate needed to form the nucleotide. The breakdown or catabolism of pyrimidine leads to several products, that can be used for fatty acid synthesis or enter the urea cycle; while the breakdown of purine nucleotides leads to one final product, uric acid, which is insoluble and excreted in urine. High levels of uric acid can lead to gout, which involves the accumulation of uric acid crystals in joints. Deficiency or genetic defects in the enzymes involved in nucleotide metabolism often results in several diseases, such as deficiency of adenine deaminase, which leads to severe combined immunodeficiency (SCID).
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CANT1 Polyclonal Antibody, FITC Conjugated
CANT1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A55892-05050 µg $256.00 Add to Cart
A55892-100100 µg $359.00 Add to Cart
Antibodies
CANT1 Polyclonal Antibody, HRP Conjugated
CANT1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A55891-05050 µg $256.00 Add to Cart
A55891-100100 µg $359.00 Add to Cart
Antibodies
CDA Polyclonal Antibody
CDA Polyclonal Antibody

Application: ELISA, IF, IHC, WB
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A52901-02020 µg $59.00 Add to Cart
A52901-05050 µg $256.00 Add to Cart
A52901-100100 µg $359.00 Add to Cart
Antibodies
CDA Polyclonal Antibody, Biotin Conjugated
CDA Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A52904-05050 µg $256.00 Add to Cart
A52904-100100 µg $359.00 Add to Cart
Antibodies
CDA Polyclonal Antibody, FITC Conjugated
CDA Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A52903-05050 µg $256.00 Add to Cart
A52903-100100 µg $359.00 Add to Cart
Antibodies
CDA Polyclonal Antibody, HRP Conjugated
CDA Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A52902-05050 µg $256.00 Add to Cart
A52902-100100 µg $359.00 Add to Cart
Antibodies
cmk Polyclonal Antibody
cmk Polyclonal Antibody

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Escherichia coli
Trial Size Available: Yes
A50845-02020 µg $59.00 Add to Cart
A50845-05050 µg $256.00 Add to Cart
A50845-100100 µg $359.00 Add to Cart
Antibodies
cmk Polyclonal Antibody, Biotin Conjugated
cmk Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Escherichia coli
A50848-05050 µg $256.00 Add to Cart
A50848-100100 µg $359.00 Add to Cart
Antibodies
cmk Polyclonal Antibody, FITC Conjugated
cmk Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Escherichia coli
A50847-05050 µg $256.00 Add to Cart
A50847-100100 µg $359.00 Add to Cart
Antibodies
cmk Polyclonal Antibody, HRP Conjugated
cmk Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Escherichia coli
A50846-05050 µg $256.00 Add to Cart
A50846-100100 µg $359.00 Add to Cart
Antibodies
CTPS1 Polyclonal Antibody
CTPS1 Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A50153-02020 µg $59.00 Add to Cart
A50153-05050 µg $256.00 Add to Cart
A50153-100100 µg $359.00 Add to Cart
Antibodies
CTPS1 Polyclonal Antibody, Biotin Conjugated
CTPS1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A50156-05050 µg $256.00 Add to Cart
A50156-100100 µg $359.00 Add to Cart
Antibodies
CTPS1 Polyclonal Antibody, FITC Conjugated
CTPS1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A50155-05050 µg $256.00 Add to Cart
A50155-100100 µg $359.00 Add to Cart
Antibodies
CTPS1 Polyclonal Antibody, HRP Conjugated
CTPS1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A50154-05050 µg $256.00 Add to Cart
A50154-100100 µg $359.00 Add to Cart
Antibodies
CTPS2 Polyclonal Antibody
CTPS2 Polyclonal Antibody

Application: ELISA, IHC, IP, WB
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A67302-02020 µg $59.00 Add to Cart
A67302-05050 µg $256.00 Add to Cart
A67302-100100 µg $359.00 Add to Cart
Antibodies
CTPS2 Polyclonal Antibody, Biotin Conjugated
CTPS2 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A67305-05050 µg $256.00 Add to Cart
A67305-100100 µg $359.00 Add to Cart
Antibodies
CTPS2 Polyclonal Antibody, FITC Conjugated
CTPS2 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A67304-05050 µg $256.00 Add to Cart
A67304-100100 µg $359.00 Add to Cart
Antibodies
CTPS2 Polyclonal Antibody, HRP Conjugated
CTPS2 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A67303-05050 µg $256.00 Add to Cart
A67303-100100 µg $359.00 Add to Cart
Antibodies
deoD Polyclonal Antibody
deoD Polyclonal Antibody

Application: ELISA, WB
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Escherichia coli
Trial Size Available: Yes
A53072-02020 µg $59.00 Add to Cart
A53072-05050 µg $256.00 Add to Cart
A53072-100100 µg $359.00 Add to Cart
Antibodies
deoD Polyclonal Antibody, Biotin Conjugated
deoD Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Metabolism
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Escherichia coli
A53069-05050 µg $256.00 Add to Cart
A53069-100100 µg $359.00 Add to Cart
Antibodies
Result Pages: [<< Prev]   1  2  3  4  5 ...  [Next >>]  Displaying 21 to 40 (of 211 products)
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