BackgroundCatalyzes the first irreversible step in ketogenesis, condensing acetyl-CoA to acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate.
DescriptionHMGCS2 Recombinant Monoclonal Antibody [19C11]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP54868
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human HMGCS2
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesHydroxymethylglutaryl-CoA synthase, mitochondrial (HMG-CoA synthase) (EC 2.3.3.10) (3-hydroxy-3-methylglutaryl coenzyme A synthase), HMGCS2
ApplicationELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:50-1:200
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