BackgroundThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.
DescriptionUBE2D3 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDP61077
PurificationAffinity Purification
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 1-100 of human UBE2D3 (NP_003331.1).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesUBE2D3; E2(17)KB3; UBC4/5; UBCH5C; ubiquitin-conjugating enzyme E2 D3
ApplicationWB; Recommended dilution: WB: 1:500-1:2000