BackgroundThrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
DescriptionTHBD Recombinant Monoclonal Antibody [15C7]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP07204
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human THBD
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesThrombomodulin (TM) (Fetomodulin) (CD antigen CD141), THBD, THRM
ApplicationELISA, IHC; Recommended dilution: IHC:1:50-1:200
Celebrate our 20th year anniversary with gifts on purchases above $300!
» Learn more
Cart (0)
