BackgroundThis is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.
DescriptionPRLR Recombinant Monoclonal Antibody [1D3]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman, Mouse
IsotypehIgG2
Uniprot IDP16471
PurificationAffinity Chromatography
ImmunogenRecombinant Human PRLR protein
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesPRLR; Prolactin receptor; PRL-R
ApplicationELISA
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