BackgroundThis gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants.
DescriptionPFKP Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDQ01813
PurificationAffinity Purified
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 336-540 of human PFKP (NP_002618.1)
StorageShipped at 4°C. Store at -20°C. Avoid freeze / thaw cycles.
Alternative NamesPFKP; ATP-PFK; PFK-C; PFK-P; PFKF
ApplicationWB, IHC, IF; Recommended dilution: WB 1:500 - 1:2000, IHC 1:100 - 1:200, IF 1:50 - 1:200