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PCAF Polyclonal Antibody

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Immunohistochemistry of paraffin-embedded human melanoma using PCAF Polyclonal Antibodyat dilution of 1:100
Application: ELISA, IHC
Areas of Research: Histone Acetylation & Deacetylation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A-4012-02020 µg $99.00 
A-4012-05050 µg $204.00 
A-4012-100100 µg $391.00 
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Product Overview

Background
PCAF (P300/CBP-associated factor) has been identified in several species and is a nuclear histone acetylase which plays a role in the regulation of transcription, cell cycle progression and differentiation. Human PCAF is a ubiquitous protein member of the GCN5-related histone acetyltransferas superfamily. PCAF interacts with P300 and CBP transcriptional cofactors and acetylates all 4 core-histones. Also, it has been also shown to acetylate various other proteins, including the transcription factors p53 and p65.

Description
PCAF Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, pH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
Q92831

Purification
Protein G purified

Immunogen
Recombinant Human Histone acetyltransferase KAT2B protein (767-832AA)

Storage
Shipped at 4°C (Blue Ice)

Alternative Names
CAF antibody, CREBBP associated factor antibody, GCN5 antibody, GCN5L antibody, GCN5L1 antibody, Histone acetylase PCAF antibody, Histone acetyltransferase KAT2B antibody, Histone acetyltransferase PCAF antibody, K(lysine) acetyltransferase 2B antibody, KAT2B antibody, Lysine acetyltransferase 2B antibody, P antibody, p300/CBP associated factor antibody

Application
ELISA, IHC; Recommended dilution: IHC:1:20-1:200

User Guide & MSDS

[User Guide]*
*Always use the actual User Guide that shipped with your product. Is the above file locked? You can also request user guides by emailing info@epigentek.com along with your contact information and institution name.

[Safety Data Sheet]
Product Citations

Xiong Y et. al. (June 2014). Differential Coupling of KLF10 to Sin3-HDAC and PCAF Regulates the Inducibility of the FOXP3 Gene. Am J Physiol Regul Integr Comp Physiol.

Introduction to Epigenetics
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