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Histone Phosphorylation Assay

Histone phosphorylation of histone H3 at serine 10 and serine 28 is conserved through eukaryotes, and an increase in phosphorylation has been shown to correlate with gene activation and cell growth. Detection of changes in histone phosphorylation levels can provide useful information in better understanding the pathological processes of some diseases, and for protein kinase-targeted drug development.
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