Use code E2503HDH to take 30% Off our HDAC & HAT Assay Kits (96 assay sizes only) through April*
Histone acetyltransferases (HATs) and deacetylases (HDACs) are two classes of enzymes that catalyze reversible histone acetylation. Identifying and determining the distribution of HAT or HDAC activities can further our knowledge of cellular regulation and response. EpiGentek offers several ready-to-use kits that measure histone acetyltransferase or histone deacetylases levels quickly and safely.
Schematic procedure for the Epigenase™ HDAC Activity/Inhibition Direct Assay Kit (Cat# P-4034).
About Histone Acetylation and Deacetylation
The balance between protein acetylation and deacetylation regulates several physiological and pathological cellular processes, and the enzymes involved in the maintenance of this equilibrium -- histone acetyltransferases (HATs) and histone deacetylases (HDACs) -- have been widely studied. Presently, the evidence obtained in this field suggests that the dynamic acetylation equilibrium is primarily maintained through the physical and functional exchange between HAT and HDAC activities.
Directly detects HDAC-converted deacetylated products rather than trypsin-based peptide cleavage
Uses cell/tissue extracts or purified HDAC enzymes for in vivo and in vitro detection
Detection from as low as 0.5 ng of purified HDAC enzyme
Includes a potent inhibitor of class I & II HDAC activity as the positive control
Flexible strip-well microplate format for manual or high throughput analysis
Catalog #s: P-4034 & P-4035*
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EpiQuik HDAC1 -7 Assay Kits
Measure the total amount of HDAC 1-11 proteins quantitatively through an ELISA-like method
No need for electrophoresis
Detection limit as low as 0.2 ng of HDAC protein
Flexible strip-well microplate format for manual or high throughput analysis
Catalog #s: See Cat#s
*30% savings offer applies to our HDAC and HAT kits (96 assays sizes only) with code E2503HDH. Orders must include the code to receive the discount. No retroactive discounts are allowed. Offer valid for US customers only. Not available to distributors or resellers. Cannot be combined with other offers. Expires on April 30, 2025.
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Histone acetyltransferases (HATs) and deacetylases (HDACs) are two classes of enzymes that catalyze reversible histone acetylation. Identifying and determining the distribution of HAT or HDAC activities can further our knowledge of cellular regulation and response. EpiGentek offers several ready-to-use kits that measure 
