BackgroundPart of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
DescriptionMPO Recombinant Monoclonal Antibody [2G11]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP05164
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human Myeloperoxidase
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesMyeloperoxidase (MPO) (EC 1.11.2.2) [Cleaved into: Myeloperoxidase, 89 kDa myeloperoxidase, 84 kDa myeloperoxidase, Myeloperoxidase light chain, Myeloperoxidase heavy chain], MPO
ApplicationELISA, IHC; Recommended dilution: IHC:1:50-1:200