UL48 Polyclonal Antibody, HRP Conjugated

Background
Transcriptional activator of immediate-early (IE) gene products (alpha genes). Acts as a key activator of lytic infection by initiating the lytic program through the assembly of the transcriptional regulatory VP16-induced complex composed of VP16 and two cellular factors, HCFC1 and POU2F 1. VP16-induced complex represents a regulatory switch: when it is on, it promotes IE-gene expression and thus lytic infection, and when it is off, it limits IE-gene transcription favoring latent infection.

Description
UL48 Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human herpesvirus 1

Isotype
IgG

Uniprot ID
P04486

Purification
>95%, Protein G purified

Immunogen
Recombinant Human herpesvirus 1 Tegument protein VP16 protein (1-490AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
Tegument protein VP16, Alpha trans-inducing protein, Alpha-TIF, ICP25, Vmw65, UL48

Application
ELISA; Recommended dilution: ELISA 1:500-1:1000