BackgroundUDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.
DescriptionUGT2B4 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDP06133
Purification>95%, Protein G purified
ImmunogenRecombinant Human UDP-glucuronosyltransferase 2B4 protein (281-481AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesUDP-glucuronosyltransferase 2B4 (EC:2.4.1.17), UDPGT 2B4, UGT2B4, UGT2B11, HLUG25, Hyodeoxycholic acid-specific UDPGT, UDPGTh-1
ApplicationELISA, IHC; Recommended dilution: IHC:1:20-1:200