BackgroundPlays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.
DescriptionKLRG1 Recombinant Monoclonal Antibody [8E11]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDQ96E93
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human KLRG1
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesKiller cell lectin-like receptor subfamily G member 1 (C-type lectin domain family 15 member A) (ITIM-containing receptor MAFA-L) (MAFA-like receptor) (Mast cell function-associated antigen), KLRG1, CLEC15A MAFA MAFAL
ApplicationELISA, FC; Recommended dilution: FC:1:50-1:200