BackgroundJunctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH1 contributes to the construction of the skeletal muscle triad by linking the t-tubule (transverse-tubule) and SR (sarcoplasmic reticulum) membranes.
DescriptionJPH1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, pH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ9HDC5
Purification>95%, Protein G purified
ImmunogenRecombinant Human Junctophilin-1 protein (431-546AA)
StorageShipped at 4°C. Upon receipt, store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesJunctophilin-1, JP-1, Junctophilin type 1, JPH1, JP1
ApplicationELISA, IHC, IF; Recommended dilution: IHC: 1:200-1:500, IF: 1:50-1:200