BackgroundThis neurotoxin binds at site 3 of insect voltage-activated sodium channels (Nav) and prolongs evoked axonal action potentials by a slowing down of sodium current inactivation. The toxin inhibits glutamate uptake from rat brain synaptosomes. It is highly toxic to house fly (Musca domestica), toxic to cockroach, but has no effect when intracerebroventricularly injected into mice.
DescriptionDelta-Ctenitoxin-Pn1a Polyclonal Antibody, HRP Conjugated. HRP. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityPhoneutria nigriventer
IsotypeIgG
Uniprot IDP59368
Purification>95%, Protein G purified
ImmunogenRecombinant Phoneutria nigriventer Delta-ctenitoxin-Pn1a protein (35-82AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesDelta-ctenitoxin-Pn1a, Delta-CNTX-Pn1a
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000