Speed through Protein/RNA Interaction Studies with CUT&LUNCH RIP
RNA Immunoprecipitation (RIP) profiles protein-RNA interactions, but traditional workflows can be lengthy, variable, and limited in resolution. The low-cost EpiNext™ CUT&LUNCH RNA Immunoprecipitation (RIP) Kit enables rapid, highly specific enrichment of targeted protein-RNA complexes.
✓Rapid Protocol: Complete your assay in less than 2 hours.
✓Low Background: Non-specific protein-RNA complexes are selectively eliminated.
✓High Specificity & Resolution: Only antibody-bound complexes are recovered.
✓Cost-effective: Less than half the price per reaction versus competitor RIP products.
What is CUT&LUNCH?
CUT&LUNCH stands for Cleavage Under Target and Liberate Unique Nucleic Complex Homogeneously. It is an antibody-guided, controlled-cleavage workflow designed to isolate target-associated nucleic acid complexes with high specificity. Adapted for RIP, the method selectively removes non-target RNA complexes while preserving and recovering antibody-bound protein-RNA complexes for downstream analysis.
Extremely Fast 3-Step Protocol
Compare CUT&LUNCH RIP vs Traditional RIP Kits
Feature
CUT&LUNCH RIP Kit EpigenTek
RIP Kit Supplier A
RIP Kit Supplier M
Workflow Convenience
✅ Streamlined (total 20 steps)
❌ Labor-intensive (>50 steps)
❌ Labor-intensive (40 steps)
Protocol Time
✅ Fast (1 hr 50 min)
❌ Slow (1-2 days)
❌ Slow (8 hrs to 2 days)
Required Cell Amount
✅ Low (50K-1M)
❌ High (15M)
❌ High (20M)
Sequence Resolution
✅ High (enzymatic cleavage at both ends of RNA)
❌ Lower (sonication → RNA fragments of varying length)
