BackgroundCatalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
DescriptionIMPDH2 Polyclonal Antibody, Biotin Conjugated. Biotin. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDP12268
Purification>95%, Protein G purified
ImmunogenRecombinant Human Inosine-5'-monophosphate dehydrogenase 2 protein (5-514AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesInosine-5'-monophosphate dehydrogenase 2UniRule annotation, IMPDH2, IMPDH-II
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000
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