GUCY2C Recombinant Monoclonal Antibody [4G12]

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The Binding Activity of Huamn GUCY2C with Anti-GUCY2C recombinant Antibody.
Activity: Measured by its binding ability in a functional ELISA. Immobilized human GUCY2C at 5 ug/mL can bind Anti-GUCY2C recombinant antibody, the EC₅₀ is 3. 049-4. 660 ng/mL.

T84 cells were stained with Mouse IgG2a (green line) and anti-GUCY2C antibody (red line) (2µg/1*10⁶cells), washed and then followed by FITC-conjugated Goat Anti-Mouse IgG(H+L) antibody and analyzed with flow cytometry.

Untransfected CT26 cells (green line) and transfected Human GUCY2C CT26 stable cells (red line) were stained with anti-GUCY2C antibody (2µg/1*10⁶cells), washed and then followed by FITC-conjugated Goat Anti-Mouse IgG(H+L) antibody and analyzed with flow cytometry.

Application:	ELISA, FC
Areas of Research:	Cell Surface Receptor & Kinase
Clonality:	Monoclonal
Conjugate:	Unconjugated
Host:	HEK293F Cell
Isotype:	mIgG2a
Purification:	Affinity Chromatography
Reactivity:	Human
Recombinant:	Yes
100% Guarantee:	6 months

Catalog No.	Size	Price	Qty
A74086-050	50µl	$299.00
A74086-100	100µl	$399.00

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Product Overview
Datasheet & SDS
Product FAQ

Product Overview

Background
Guanylyl cyclase that catalyzes synthesis of cyclic GMP (cGMP) from GTP. Receptor for the E.coli heat-stable enterotoxin; E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GUCY2C. Also activated by the endogenous peptides guanylin and uroguanylin.

Description
GUCY2C Recombinant Monoclonal Antibody [4G12]. Unconjugated. Raised in: HEK293F Cell.

Formulation
Buffer: 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
mIgG2a

Uniprot ID
P25092

Purification
Affinity Chromatography

Immunogen
Recombinant Human GUCY2C protein

Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Alternative Names
GC-C; Guanylyl cyclase C; GUC2C; GUC2C_HUMAN; GUCY2C; Heat stable enterotoxin receptor; Heat-stable enterotoxin receptor; hSTAR; Intestinal guanylate cyclase; STA receptor

Application
ELISA, FC; Recommended dilution: FC:1:50-1:200

Datasheet & SDS

Datasheet/User Guide
If the above file is not available online, you can request a copy by contacting us.

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GUCY2C Recombinant Monoclonal Antibody [4G12]