BackgroundApoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.
DescriptionCRADD Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Formulation0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4
SpecificityHuman
IsotypeIgG
Uniprot IDP78560
PurificationProtein G purified
ImmunogenRecombinant Human Death domain-containing protein CRADD protein (1-199AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesCaspase and RIP adapter with death domain, RIP-associated protein with a death domain, CRADD, RAIDD
ApplicationELISA, IF; Recommended dilution: IF:1:500-1:1000