BackgroundComponent of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function (PubMed:23704930), (PubMed:25764979).
DescriptionAPOOL Polyclonal Antibody, Biotin Conjugated. Biotin. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ6UXV4
Purification>95%, Protein G purified
ImmunogenRecombinant Human MICOS complex subunit MIC27 protein (163-268AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesMICOS complex subunit MIC27, Apolipoprotein O-like, Protein FAM121A, APOOL, CXorf33, FAM121A, MIC27, UNQ8193/PRO23204
ApplicationELISA; Recommended dilution: ELISA 1:500-1:1000