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Introduction to Epigenetics

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HP1-gamma Polyclonal Antibody
HP1-gamma Polyclonal Antibody

SUV39H2 Polyclonal Antibody

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Application: ChIP, IHC, IP, WB
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse
Application Guarantee: 6 months
Catalog No.SizePriceQty
A-3010-05050 µg $229.00 
A-3010-100100 µg $389.00 
Availability: Usually Ships In 1-2 Days 
Product Overview

Background
SUV39H2 encodes a H3 HMTase that shares 59% identity with SUV39H1, but which differs by the presence of a highly basic N terminus. SUV39H2 is also responsible for creating HP1 binding sites in heterochromatin by methylation of histone H3-Lys9. Moreover, SUV39H2 specifically accumulates with chromatin of the sex chromosomes (XY body), which undergo transcriptional silencing during the first meiotic prophase.

Concentration
1 mg/ml

Description
Rabbit polyclonal antibody to SUV39H2, ChIP-grade

Purification
Affinity purification

Specificity
Human, mouse

Immunogen 
Recombinant protein of human SUV39H2

Isotype 
IgG

Formulation 
PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage
Store at -20ºC (regular) or -80ºC (long term). Avoid freeze / thaw cycles

Alternative Names
FLJ23414 antibody, H3 K9 HMTase 2 antibody, Histone H3 K9 methyltransferase 2 antibody, Histone lysine N methyltransferase H3 lysine 9 specific 2 antibody, Histone lysine N methyltransferase SUV39H2 antibody, KMT1B antibody, Lysine N methyltransferase 1B antibody, sSuppressor of variegation 3 9 homolog 2 (Drosophila) antibody, Su(var)3 9 Drosophila homolog of 2 antibody, Suppressor of variegation 3 9 homolog 2 antibody, Suv39h2 antibody, SUV92_HUMAN antibody

Application
WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IP: 1:50 - 1:200, ChIP: 1:20 - 1:100

Fig. 1. Western blot analysis of extracts of various cell lines, using SUV39H2 antibody

 

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