SUV39H2 encodes a H3 HMTase that shares 59% identity with SUV39H1, but which differs by the presence of a highly basic N terminus. SUV39H2 is also responsible for creating HP1 binding sites in heterochromatin by methylation of histone H3-Lys9. Moreover, SUV39H2 specifically accumulates with chromatin of the sex chromosomes (XY body), which undergo transcriptional silencing during the first meiotic prophase.
Rabbit polyclonal antibody to SUV39H2, ChIP-grade
Recombinant protein of human SUV39H2
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Store at -20ºC (regular) or -80ºC (long term). Avoid freeze / thaw cycles
FLJ23414 antibody, H3 K9 HMTase 2 antibody, Histone H3 K9 methyltransferase 2 antibody, Histone lysine N methyltransferase H3 lysine 9 specific 2 antibody, Histone lysine N methyltransferase SUV39H2 antibody, KMT1B antibody, Lysine N methyltransferase 1B antibody, sSuppressor of variegation 3 9 homolog 2 (Drosophila) antibody, Su(var)3 9 Drosophila homolog of 2 antibody, Suppressor of variegation 3 9 homolog 2 antibody, Suv39h2 antibody, SUV92_HUMAN antibody
WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IP: 1:50 - 1:200, ChIP: 1:20 - 1:100
Fig. 1. Western blot analysis of extracts of various cell lines, using SUV39H2 antibody