Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Rabbit polyclonal antibody raised against a synthetic peptide corresponding to the N-terminus of histone H3 acetylated on K18, ChIP-grade
Broad Range, Mouse, Rat, Human
A synthetic acetylated peptide corresponding to residues surrounding K18 of human H3
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Store at -20°C or -80°C. Avoid freeze / thaw cycles.
H3K18ac antibody; H3K18a antibody;H3t; H3.4; H3/g; H3FT
WB 1:1000 - 1:3000
IHC 1:200- 1:500
IF 1:500- 1:1000
IP 1:200- 1:500
ChIP 1:50- 1:100
ChIP-Seq 1:50- 1:100
Fig. 1. Western blot analysis of extracts of various cell lines, using Histone H3K18ac (Acetyl H3K18) Polyclonal Antibody.