DNMT3B has been demonstrated to methylate both unmethylated and hemimethylated DNA equally and is supposed to mediate de novo methylation together with Dnmt1. Increased activation or amount of Dnmt3b is believed to be involved in carcinogenesis, as well as other genetic and epigenetic diseases.
Rabbit polyclonal antibody to Dnmt 3b, ChIP-grade
Protein A purified
Mouse, rat, human
0.1% Sodium Azide, 0.1% Gelatin, PBS
4°C, stable for 1 year from the date of shipment. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance.
Cytosine 5methyltransferase 3B antibody, DNA (cytosine 5) methyltransferase 3 beta antibody, DNA (cytosine-5)-methyltransferase 3B antibody, DNA antibody, DNA methyltransferase HsaIIIB antibody, DNA MTase HsaIIIB antibody, DNM3B_HUMAN antibody, Dnmt3b antibody, EC 220.127.116.11 antibody, ICF antibody, ICF1 antibody, M.HsaIIIB antibody, MGC124407 antibody, RP23-89H14.3 antibody
WB: 1:200-1:500; IF: 1:100-1:500; ELISA: 1:1000-1:2000; IP: 2 µg/106 cells
Fig. 1. Western Blot analysis of DNMT3B (#A-1004, 1:1000) antibody with T47D cells.