Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome.
Rabbit polyclonal antibody to the dimethylated histone H3 at K79, ChIP-grade
A synthetic peptide of human Histone H3K79me2
Human, mouse, rat and broad range
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.
H3.4; H3/g; H3FT; H3t; MGC126886; MGC126888; H3K79me2 antibody; H3K79m2 antibody
WB: 1:500 - 1:1000, IHC: 1:50 - 1:100, IF: 1:50 - 1:200, IP: 1:50 - 1:200, ChIP: 1:50 - 1:200, ChIP-seq: 1:50-1:200