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p300 Polyclonal Antibody

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Application: ChIP, ELISA, IF, IHC, IP, WB
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
Application Guarantee: 6 months
Catalog No.SizePriceQty
A-4020-05050 µg $199.00 
A-4020-100100 µg $369.00 
Availability: Usually Ships In 1-2 Days 
Product Overview

Background
p300, also known as EP300 or E1A binding protein p300, is a universally expressed, reasonably stable nuclear phosphorprotein that is closely related to CBP (or CREB). CBP and p300 are identified as transcriptional coactivators that can directly interact with several different DNA-binding transcription factors including nuclear hormone receptors, CREB, c-Fos, C-Jun/v-Jun, c-Myb/v-Myb, TFIIB and MyoD. These two proteins have been known to exhibit histone acetyltransferase (HAT) activity and can acetylate all four core histones in the nucleosome. It is believed that both p300 and CBP may be directly involved in activating chromatin for transcription.

Concentration
2 mg/ml

Description
Rabbit polyclonal antibody to p300, ChIP-grade

Purification
Protein A purified

Specificity
Mouse, rat, human

Isotype
IgG

Formulation 
0.1% Sodium Azide, PBS

Storage
4ºC, stable for 1 year from the date of shipment. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance

Alternative Names
CREBBP/EP300 inhibitory protein 1 antibody, P-300, Cyclic AMP responsive enhancer binding protein antibody, E1A associated protein p300 antibody, E1A binding protein p300 antibody, EC 2.3.1.48 antibody, EP300 antibody, Histone acetyltransferase p300 antibody, p300 HAT antibody, RB and P300 binding protein EID 1 antibody, Retinoblastoma protein associated protein antibody, RSTS2 antibody

Application 
WB: 1:2000-1:10000, IF: 1:500-1:5000, IHC: 1:500-1:5000, ELISA: 1:300-1:30000, IP: 0.2 μg/10^6 cells

Fig. 1. WB analysis of p300 Polyclonal Antibody with KNRK cell lysates (A-4020).

 

User Guide & MSDS

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