Epigentek Home
 
Epigentek Free Shipping

DNMT3A Polyclonal Antibody

Share:

Citations (2) | Write a Review
Western blot analysis of extracts of various tissues, using DNMT3A Polyclonal Antibody.
Immunofluorescence analysis of A549 cell using DNMT3A Polyclonal Antibody. Blue: DAPI for nuclear staining.
Application: IF, IHC, WB
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
Guarantee: 6 months
Catalog No.SizePriceQty
A-1003-05050 µg $199.00 
A-1003-100100 µg $369.00 
Availability: Usually Ships in 3-4 Days 
Product Overview

Background
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.

Concentration
0.2 mg/ml

Description
Rabbit polyclonal antibody to Dnmt 3a

Immunogen 
Recombinant protein of human DNMT3A

Purification
Affinity purification

Specificity
Mouse, rat, human

Isotype
IgG

Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage
Store at -20ºC (regular) or -80ºC (long term). Avoid freeze / thaw cycles

Alternative Names
DNA (cytosine 5) methyltransferase 3 alpha antibody, DNA (cytosine-5)-methyltransferase 3A antibody, DNA cytosine methyltransferase 3A2 antibody, DNA methyltransferase 3a antibody, DNA methyltransferase HsaIIIA antibody, DNA MTase HsaI antibody, DNA MTase HsaIIIA antibody, DNM3A_HUMAN antibody, DNMT 3a antibody, DNMT antibody, DNMT3A2 antibody, M HsaIIIA antibody, MCMT antibody, Methyl CpG binding domain protein 3a antibody, OTTHUMP00000201149 antibody,DNMT3A2, M.HsaIIIA

Application:
WB: 1:50 - 1:200, IHC: 1:50 - 1:200, IF: 1:50 - 1:200 


Fig. 1.  Western blot analysis of extracts of various tissues, using DNMT3A Polyclonal Antibody.


Fig. 2.  Immunofluorescence analysis of A549 cell using DNMT3A Polyclonal Antibody. Blue: DAPI for nuclear staining.

User Guide & MSDS

[User Guide]*
*Always use the actual User Guide that shipped with your product. Is the above file locked? You can also request user guides by emailing info@epigentek.com along with your contact information and institution name.

Product Citations

Ng EK et. al. (August 2009). MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer. Br J Cancer. 101(4):699-706.

Socha MJ et. al. (February 2009). Aberrant promoter methylation of SPARC in ovarian cancer. Neoplasia. 11(2):126-35.

Epigentek Rewards

Researchers Also Purchased
DNMT3B Polyclonal Antibody
DNMT3B Polyclonal Antibody
DNMT1 Monoclonal Antibody [60B1220.1]
DNMT1 Monoclonal Antibody [60B1220.1]
DNMT1 Polyclonal Antibody
DNMT1 Polyclonal Antibody
5-Methylcytosine (5-mC) Monoclonal Antibody [33D3]
5-Methylcytosine (5-mC) Monoclonal Antibody [33D3]
Epigentek is an epigenetics company that specializes in epigenetic kits, antibodies, reagents, and services for epigenetic research in DNA methylation, histone modification, and chromatin studies. Terms & Conditions | Privacy Policy | Site Map
Copyright © 2016 Epigentek Group Inc. All rights reserved.