Epigentek Home
 
Epigentek Free Shipping

MGMT Polyclonal Antibody

Share:

Write a Review
Application: ChIP, ELISA, IF, IP, WB
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
Application Guarantee: 6 months
Catalog No.SizePriceQty
A-1010-05050 µg $199.00 
A-1010-100100 µg $369.00 
Availability: Usually Ships in 3-4 Days 
Product Overview

Background
O6-methylguanine methyltransferase (MGMT) is a ubiquitous DNA repair protein that removes O6 -alkyl-guanine lesions, primarily O6 -methyl-guanine from damaged DNA. It is a major contributor to cellular protection from the mutagenic, carcinogenic, and cytotoxic effects of DNA alkylation. Also, MGMT is frequently silenced due to abnormal methylation during cancer development. Consequently, the loss of MGMT activity that made the cell more likely to become a cancer cell in the first place also makes tumor cells more sensitive to radiation therapy and certain alkylating drugs. 

Concentration
0.2 mg/ml

Description
Rabbit polyclonal antibody to MGMT, ChIP-grade

Purification
Protein A purified

Specificity
Mouse, rat, human

Isotype
IgG

Formulation
0.1% Sodium Azide, 0.1% Gelatin, PBS

Storage
4°C, stable for 1 year from the date of shipment. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance

Alternative Names
6 O methylguanine DNA methyltransferase antibody, Agat antibody, AGT antibody, AI267024 antibody, EC 2.1.1.63 antibody, Methylated DNA protein cysteine methyltransferase antibody, Methylguanine DNA methyltransferase antibody, MGC107020 antibody, MGMT antibody, O 6 methylguanine DNA alkyltransferase antibody, O 6 methylguanine DNA methyltransferase antibody

Application
WB: 1:200-1:500; IF: 1:100-1: 500, ELISA: 1:1000-1:2000; IP: 2 µg/106 cells

Fig. 1. WB analysis of MGMT antibody with MCF-7 nuclear extracts (A-1010).

 

User Guide & MSDS

[User Guide]*
*Always use the actual User Guide that shipped with your product. Is the above file locked? You can also request user guides by emailing info@epigentek.com along with your contact information and institution name.

Epigentek is an epigenetics company that specializes in epigenetic kits, antibodies, reagents, and services for epigenetic research in DNA methylation, histone modification, and chromatin studies. Terms & Conditions | Privacy Policy | Site Map
Copyright © 2016 Epigentek Group Inc. All rights reserved.