MBD3, or methyl-CpG binding domain protein 3, is a protein that is a member of the methyl-CpG-binding domain (MBD) family, which also includes MeCP2, MBD1, MBD2, MBD4, CLLD8-like, and BAZ2A-like proteins. Although MBD3 is a member of the methyl-CpG-binding domain family, it is not able to bind to methylated DNA. It is a subunit of a multisubunit complex known as NuRD, which is involved in nucleosome remodeling and histone deacetylase functions. It is also thought to mediate the relationship of MTA2, or metastasis-associated protein 2, with the histone deacetylase core complex.
Rabbit polyclonal antibody to MBD3
Protein A purified
Mouse, rat, human
0.1% Sodium Azide, 0.1% Gelatin, PBS
4°C, stable for 1 year from the date of shipment. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance.
AI181826 antibody, AU019209 antibody, MBD 3 antibody, MBD3: methyl CpG binding domain protein 3 antibody, MBD3_HUMAN antibody, Methyl CpG binding protein MBD3 antibody
WB: 1:200-1:500; IF: 1:100-1: 500, ELISA: 1:1000-1:2000; IP: 2 µg/10^6 cells
Fig. 1. WB analysis of MBD3 Polyclonal Antibody with 293T cells (A-1008). Lane 1: untransfected with MBD3; Lane 2: transfected with MBD3.