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EZH2 Polyclonal Antibody

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Citations (3) | Write a Review
Application: IF, IHC, WB
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
Application Guarantee: 6 months
Catalog No.SizePriceQty
A-2019-05050 µg $229.00 
A-2019-100100 µg $399.00 
Availability: Usually Ships In 1-2 Days 
Product Overview

Background 
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.

Concentration
1mg/ml

Description
Rabbit polyclonal antibody to EZH2

Immunogen 
Recombinant protein of human EZH2

Purification
Affinity purified

Specificity
Human, mouse and rat

Isotype
IgG

Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage
Store at -20ºC (regular) or -80ºC (long term). Avoid freeze / thaw cycles

Alternative Names
Enhancer of zeste homolog 2 (Drosophila) antibody, ENX 1 antibody, Enx 1h antibody, EZH1 antibody, EZH2b antibody, Histone-lysine N-methyltransferase EZH2 antibody, KMT 6 antibody, KMT6A antibody, Lysine N-methyltransferase 6 antibody, MGC9169 antibody, WVS antibody, WVS2 antibody, WVS; ENX1, EZH1, KMT6, WVS2, ENX-1, EZH2b, KMT6A

Application
WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:20 - 1:100

Fig. 1. Western blot analysis of extracts of various cell lines, using EZH2 antibody.

Fig. 2. Immunofluorescence analysis of U20S cell using EZH2 antibody. Blue: DAPI for nuclear staining.

User Guide & MSDS

[User Guide]*
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Product Citations

Colón-Caraballo M et. al. (March 2015). H3K27me3 is an Epigenetic Mark of Relevance in Endometriosis. Reprod Sci.

Chen H et. al. (October 2011). PDGF signalling controls age-dependent proliferation in pancreatic β-cells. Nature. 478(7369):349-55.

Chen H et. al. (April 2009). Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus. Genes Dev. 23(8):975-85.

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