Sitewide 2016 Summer Sale Site-wide summer sale with 10% off your order by using code E1606SUN when placing your order! » Learn More
Epigentek Home
 
Epigentek Free Shipping

Histone H4K12ac (Acetyl H4K12) Polyclonal Antibody

Share:

Citations (5) | Write a Review
Application: ELISA, IF, IHC, IP, WB
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
Application Guarantee: 6 months
Catalog No.SizePriceQty
A-4029-05050 µg $149.00 
A-4029-100100 µg $289.00 
Availability: Usually Ships In 1-2 Days 
Product Overview

Background
Histone H4- along with H2A, H2B, and H3- is involved in the structure of chromatin in eukaryotic cells. Histone H4 can undergo several different types of epigenetic modifications that influence cellular processes. These modifications including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation, occur on the N-terminal tail domains of histone H4, which results in remodeling of the nucleosome structure into an open conformation more accessible to transcription complexes. In most species, histone H4 is primarily acetylated at lysine 5, 8, 12, and 16. 

Concentration
0.2 mg/ml

Description
Rabbit polyclonal antibody raised against a synthetic peptide corresponding to N-terminus of histone H4 acetylated at K12.

Purification
Protein A purified

Specificity
Detects histone H4 only when acetylated at K12 in mouse, rat, and human

Isotype
IgG

Formulation 
PBS (pH 7.5), 0.1% gelatin

Storage
4°C, stable for 1 year from the date of shipment. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance

Alternative Names
H4K12ac antibody, H4K12a antibody

Application 
WB: 1:200-1:1000, IF: 1:100-1:500, IHC: 1:100-1:500, ELISA: 1:1000-1:2000, IP: 2 μg/106 cells

Fig. 1. WB analysis of Histone H4K12ac (Acetyl H4K12) Polyclonal Antibody with NIH-3T3 cell lysates (A-4029).

User Guide & MSDS

[User Guide]*
*Always use the actual User Guide that shipped with your product. Is the above file locked? You can also request user guides by emailing info@epigentek.com along with your contact information and institution name.

Epigentek is an epigenetics company that specializes in epigenetic kits, antibodies, reagents, and services for epigenetic research in DNA methylation, histone modification, and chromatin studies. Terms & Conditions | Privacy Policy | Site Map
Copyright © 2016 Epigentek Group Inc. All rights reserved.