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Histone H3K56ac (Acetyl H3K56) Polyclonal Antibody


Citations (2) | Write a Review
Application: ChIP, ChIP-Seq, ELISA, IP, WB
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
Application Guarantee: 6 months
Catalog No.SizePriceQty
A-4026-02525 µg $139.00 
A-4026-05050 µg $269.00 
Availability: Usually Ships In 1-2 Days 
Product Overview

Histone H3 along with H2A, H2B and H4 is involved in the structure of chromatin in eukaryotic cells. Histone H3 can undergo several different types of epigenetic modifications that influence cellular processes. These modifications, including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation, occur on the N-terminal tail domains of histone H3, which results in remodeling of the nucleosome structure into an open conformation more accessible to transcription complexes. In most species, histone H3 is primarily acetylated at lysine 9, 14, 18, 23, and can also be acetylated at lysine 56. 

1 mg/ml

Rabbit polyclonal antibody raised against a synthetic peptide corresponding to histone H3 acetylated on K56, ChIP-grade

Protein A purified

Detects histone H3 only when acetylated at K56 in mouse, rat, and human


PBS (pH 7.5), 150 mM NaCl, 30% glycerol

-20°C, stable for 1 year from the date of shipment. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance

Alternative Names
H3K56ac antibody, H3K56a antibody

WB: 1:200-1:1000, ELISA: 1:1000-1:2000 IP: 2 μg/106 cells

Fig. 1. WB analysis of Histone H3K56ac (Acetyl H3K56) Polyclonal Antibody with TSA-induced C6 cell lysates (A-4026).


User Guide & MSDS

[User Guide]*
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Product Citations

Zhang ZQ et. al. (April 2016). Epigenetic regulation of NKG2D ligands is involved in exacerbated atherosclerosis development in Sirt6 heterozygous mice. Sci Rep. 6:23912.

Elhanati S et. al. (September 2013). Multiple regulatory layers of SREBP1/2 by SIRT6. Cell Rep. 4(5):905-12.

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