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SUV39H1 Monoclonal Antibody

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Application: IP, WB
Areas of Research: Histone Methylation & Demethylation
Clonality: Monoclonal
Conjugate: Unconjugated
Host: Mouse
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
100% Guarantee: 6 months
Catalog No.SizePriceQty
A-3009-05050 µg $199.00 
A-3009-100100 µg $380.00 
Availability: Usually Ships in 3-4 Days 
Product Overview

Background 
SUV39H1 is a human homologue of the dominant Drosophila PEV modifier Su(var)3–9 and is composed of 412 amino acid residues. SUV39H1, as a histone methyltransferase, selectively methylates histone H3 on lysine 9, which generates a binding site for HP1 proteins. HP1 proteins are a family of heterochromatic adaptor molecules involved in both gene silencing and supra-nucleosomal chromatin structure. SUV39H1 plays in important role in histone modification and regulation of gene expression.

Description
SUV39H1 Monoclonal Antibody. Unconjugated. Raised in: Mouse

Purification
Affinity Purified

Specificity
Human, Mouse, Rat

Isotype 
IgG

Formulation 
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.S

Storage
Store at 4℃. Avoid freeze / thaw cycles.

Alternative Names
H3 K9 HMTase1 antibody, Histone H3 K9 methylation antibody, Histone H3 Lys 9 methylation antibody, Histone H3-K9 methyltransferase 1 antibody, KMT1 A antibody, KMT1A antibody, Lysine N methyltransferase 1A antibody, MG44 antibody, mIS6 antibody, Position-effect variegation 3-9 homolog antibody, Su(var)3 9 homolog 1 antibody, Suppressor of variegation 3 9 homolog 1 (Drosophila) antibody

Application 
WB 1:500 - 1:2000
IP 1:20 - 1:50

User Guide & MSDS

[User Guide]*
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Product Citations

Yu T et. al. (May 2017). Metformin inhibits SUV39H1-mediated migration of prostate cancer cells. Oncogenesis. 6(5):e324.

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