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Background
SET7, also known as SET 7/9, is a histone methyltransferase that specifically methylates histone H3 Lys4 (H3K4) and contains a SET domain. It acts on several non-histone as well as histone targets such as TAF10, histone H3, p53, and estrogen receptor alpha. SET7 is implicated in numerous human diseases due to its broad substrate specificity and researchers use SET7/9 as a model for investigating the mechanism of SET domain histone methyltransferases.
Concentration
0.25 mg/ml
Description
Rabbit polyclonal antibody to SET7
Purification
Protein A purified
Specificity
Positive in human
Isotype
IgG
Formulation
0.1% Sodium Azide, PBS
Storage
4ºC, stable for 6 months from the date of shipment. For long-term storage, aliquot and store at -20ºC. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance
Alternative Names
H4 K20 HMTase antibody, H4 K20 specific histone methyltransferase antibody, Lysine N-methyltransferase 5A antibody, N-lysine methyltransferase SETD8 antibody, Pr SET 7 antibody, SET 8 antibody, SET domain containing lysine methyltransferase 8 antibody, SET domain-containing protein 8 antibody, SET07 antibody, SETD 8 antibody, SETD8_HUMAN antibody
Application
WB: 1:200-1:500, IHC: 1:100, ELISA: 1:1000-1:2000
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 Fig. 1. Western blot analysis of Epigentek's SET7 antibody with SAOs-2 cell lysates.
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