PRMTs (Protein Arginine N-Methyltransferases) can monomethylate or dimethylate arginine residues by transferring methyl groups from S-adenoxylmethionine to the guanidine nitrogen of arginine. PRMT2, also called Protein Arginine N-Methyltransferase 2, methylates arginine residues in proteins, for example histone H4, STAT3, and FBL. With NCOA2, PRMT2 has been shown to act as a coactivator of transactivation mediated by the androgen receptor (AR) and also, with estrogen, PRMT2 has been shown to coactivate estrogen receptor (ER)-mediated transactivation. It may also be implicated in growth regulation processes.
Rabbit polyclonal antibody to PRMT2
Protein A purified
Positive in human
0.1% Sodium Azide, PBS
4ºC, stable for 6 months from the date of shipment. For long-term storage, aliquot and store at -20ºC. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance
ANM2_HUMAN antibody, EC 2.1.1. antibody, histone arginine N methyltransferase PRMT2 antibody, HMT 1 antibody, HMT1 (hnRNP methyltransferase S. cerevisiae) like 1 antibody, hnRNP methyltransferase like 1 antibody, Hrmt1l1 antibody, MGC111373 antibody, PRMT2 alpha antibody, PRMT2 beta antibody, PRMT2 gamma antibody, PRMT2L2 antibody, Protein arginine methyltransferase 2 antibody, Zf2 antibody
WB: 1:200-1:500, IHC: 1:100-1:200, ELISA: 1:500-1:1000
Fig. 1. WB analysis of PRMT2 Polyclonal Antibody with HaLa cell lysates (A-3002).