BackgroundKey enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro).
DescriptionXDH Recombinant Monoclonal Antibody [8A9]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP47989
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from human Xanthine Oxidase
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesXanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4), Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)], XDH, XDHA
ApplicationELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200