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Swi2/SNF2 Polyclonal Antibody

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Westernblot image of Swi2/SNF2 Polyclonal Antibody.
Immunohistochemistry of paraffin-embedded human colon using Swi2/SNF2 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human colon carcinoma using Swi2/SNF2 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of HeLa cell using Swi2/SNF2 Polyclonal Antibody.
Application: IF, IHC, WB
Areas of Research: Chromatin Remodeling
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human
100% Guarantee: 6 months
Catalog No.SizePriceQty
A-2023-05050 µg $199.00 
A-2023-100100 µg $380.00 
Availability: Usually Ships In 1-2 Days 
Product Overview

Background
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Description
Swi2/SNF2 Polyclonal Antibody. Unconjugated. Raised in: Rebbit.

Formulation
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Specificity
Human

Isotype
IgG

Uniprot ID
P51532

Purification
Affinity Purification

Immunogen
A synthetic peptide of human SMARCA4

Storage
Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycles.

Alternative Names
GAM1 antibody, Regulatory protein GAM1 antibody, Regulatory protein SWI2 antibody, RIC1 antibody, SNF2 antibody, SWI/SNF complex component SNF2 antibody, SWI2 antibody, Transcription factor TYE3 antibody, Transcription regulatory protein SNF2 antibody, TYE3 antibody, SMARCA4 Polyclonal Antibody, BAF190, BAF190A, BRG1, CSS4, MRD16, RTPS2, SNF2, SNF2L4, SNF2LB, SWI2, hSNF2b

Application
WB 1:500 - 1:2000
IHC 1:50- 1:100
IF 1:20- 1:50

 

User Guide & MSDS

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