The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
Swi2/SNF2 Polyclonal Antibody. Unconjugated. Raised in: Rebbit.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
A synthetic peptide of human SMARCA4
Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycles.
GAM1 antibody, Regulatory protein GAM1 antibody, Regulatory protein SWI2 antibody, RIC1 antibody, SNF2 antibody, SWI/SNF complex component SNF2 antibody, SWI2 antibody, Transcription factor TYE3 antibody, Transcription regulatory protein SNF2 antibody, TYE3 antibody, SMARCA4 Polyclonal Antibody, BAF190, BAF190A, BRG1, CSS4, MRD16, RTPS2, SNF2, SNF2L4, SNF2LB, SWI2, hSNF2b
WB 1:500 - 1:2000
IHC 1:50- 1:100
IF 1:20- 1:50