The RIZ/ PRDM2 gene is a member, through sequence homology, to a nuclear protein-methyltransferase (MTase) superfamily involved in chromatin-mediated gene expression. The gene produces two protein products, RIZ1 that contains a conserved MTase domain and RIZ2 that lacks this domain. RIZ1 gene expression is frequently silenced in human cancers, and the gene itself is also a common target of frameshift mutation in microsatellite-unstable cancers.
Rabbit polyclonal antibody to PRDM2
Protein A purified
Positive in human
0.1% Sodium Azide, PBS
4°C, stable for 6 months from the date of shipment. For long-term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance
GATA 3 binding protein G3B antibody, HUMHOXY 1 antibody, Lysine N methyltransferase 8 antibody, MTB ZF antibody, MTE binding protein antibody, PR domain zinc finger protein 2 antibody, PRDM 2 antibody, Retinoblastoma protein binding zinc finger protein antibody, RIZ 1 antibody, RIZ 2 antibody, RIZ antibody, RIZ-LSB antibody
IHC: 1:100-1:500, ELISA: 1:1000-1:2000
Fig. 1. WB analysis of PRDM2 Antibody with PRDM2-transfected cell lysates (A-2002).