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Introduction to Epigenetics

PCAF Polyclonal Antibody

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Application: ChIP, ELISA, IF, IP, WB
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
Application Guarantee: 6 months
Catalog No.SizePriceQty
A-4012-05050 µg $199.00 
A-4012-100100 µg $369.00 
Availability: Usually Ships In 1-2 Days 
Product Overview

background
PCAF (P300/CBP-associated factor) has been identified in several species and is a nuclear histone acetylase which plays a role in the regulation of transcription, cell cycle progression and differentiation. Human PCAF is a ubiquitous protein member of the GCN5-related histone acetyltransferas superfamily. PCAF interacts with P300 and CBP transcriptional cofactors and acetylates all 4 core-histones. Also, it has been also shown to acetylate various other proteins, including the transcription factors p53 and p65. 

Concentration
0.2 mg/ml

Description
Rabbit polyclonal antibody to PCAF, ChIP-grade

Purification
Protein A purified

Specificity
Mouse, rat, human

Isotype 
IgG

Formulation 
0.1% Sodium Azide, 0.1% gelatin, PBS

Storage 
4ºC, stable for 1 year from the date of shipment. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance.

Alternative Names
CAF antibody, CREBBP associated factor antibody, GCN5 antibody, GCN5L antibody, GCN5L1 antibody, Histone acetylase PCAF antibody, Histone acetyltransferase KAT2B antibody, Histone acetyltransferase PCAF antibody, K(lysine) acetyltransferase 2B antibody, KAT2B antibody, Lysine acetyltransferase 2B antibody, P antibody, p300/CBP associated factor antibody

Application
WB: 1:200-1:500, IF: 1:100-1:200, ELISA: 1:500-1:1000, IP: 2 μg/106 cells

Fig. 1. WB analysis of PCAF Polyclonal Antibody with recombinant PCAF protein (A-4012).

 

User Guide & MSDS

[User Guide]*
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Product Citations

Xiong Y et. al. (June 2014). Differential Coupling of KLF10 to Sin3-HDAC and PCAF Regulates the Inducibility of the FOXP3 Gene. Am J Physiol Regul Integr Comp Physiol.

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