PCAF (P300/CBP-associated factor) has been identified in several species and is a nuclear histone acetylase which plays a role in the regulation of transcription, cell cycle progression and differentiation. Human PCAF is a ubiquitous protein member of the GCN5-related histone acetyltransferas superfamily. PCAF interacts with P300 and CBP transcriptional cofactors and acetylates all 4 core-histones. Also, it has been also shown to acetylate various other proteins, including the transcription factors p53 and p65.
Rabbit polyclonal antibody to PCAF, ChIP-grade
Protein A purified
Mouse, rat, human
0.1% Sodium Azide, 0.1% gelatin, PBS
4ºC, stable for 1 year from the date of shipment. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance.
CAF antibody, CREBBP associated factor antibody, GCN5 antibody, GCN5L antibody, GCN5L1 antibody, Histone acetylase PCAF antibody, Histone acetyltransferase KAT2B antibody, Histone acetyltransferase PCAF antibody, K(lysine) acetyltransferase 2B antibody, KAT2B antibody, Lysine acetyltransferase 2B antibody, P antibody, p300/CBP associated factor antibody
WB: 1:200-1:500, IF: 1:100-1:200, ELISA: 1:500-1:1000, IP: 2 μg/106 cells
Fig. 1. WB analysis of PCAF Polyclonal Antibody with recombinant PCAF protein (A-4012).