BackgroundUBE2C (ubiquitin-conjugating enzyme E2C) is a protein coding gene. Proteins modified with ubiquitin are able to target abnormal or short-lived proteins for degradation. Ubiquitination uses three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). UBE2C is necessary for the elimination of mitotic cyclins and for cell cycle progression, and is believed to be involved in cancer growth. Several transcript variants encoding different isoforms have been identified for this gene. Pseudogenes of this gene have been found on chromosomes 4, 14, 15, 18, and 19.
DescriptionUBE2C Polyclonal Antibody . Unconjugated. Raised in: Rabbit.
FormulationPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDO00762
PurificationAffinity Purified
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-179 of human UBE2C (NP_008950.1)
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid repeated freeze.
Alternative NamesUBCH10, dJ447F3.2
ApplicationWB, IHC, IF, IP; Recommended dilution: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 IP 1:20 - 1:50